Tomographic imaging study of human brain corpus striatum and hippocampus structure
Chinese Journal of Clinical Anatomy ›› 2015, Vol. 33 ›› Issue (4) : 393-398.
Tomographic imaging study of human brain corpus striatum and hippocampus structure
Objective To investigate the correlation between corpus striatum and hippocampus structure, and provide the morphological evidence and related measurement value for clinical imaging diagnosis. Methods Magnetic resonance images of 100 cases of adult heads without pathological changes were collected and divided into five groups falling into five age ranges : 16 ~ 25, 26 ~ 35, 36 ~ 45, 46 ~ 55, 56 ~ 65 years old, with 10 males and 10 females in each age range. Parameters such as the area, the transverse and vertical diameter of the corpus striatum and hippocampus were obtained and underwent statistical analyses. Results After standardization of data, the outcome of the single factor analysis of variance showed: There was no gender difference in striatum area; The sagittal diameter of caudate head, the hippocampus area, and the transverse and sagittal diameter of the hippocampal structure exhibited gender difference ( female>male ); The width of the temporal horn of the male was larger than the female；The transverse diameter of the caudate nucleus head exhibited side difference (left>right)，while the right putamen area and the sagittal diameter was greater than on the left. Pearson correlation analysis showed: The head of caudate nucleus area was negatively related with age and the distance between the temporal lobe hooks, but was positively related with the width of the temporal horn. The hippocampal area was positively related with the head of caudate nucleus area and the width of the temporal horn. Conclusion The adult corpus striatum shrank with the increase of age; There was correlation between the hippocampus structure and corpus striatum on the morphology. The right putamen area was greater than the left. The female hippocampus area was greater than the male. The width of the temporal horn can be used as common references indicators in morphological research of the striatum and hippocampus.
Corpus striatum / Hippocampus structure / Sectional and imaging anatomy / MRI
[1] Herrero MT, Barcia C, Navarw JM. Functional anatomy of thalamus and basal ganglia [J].Childs Nerv Syst，2002,18(8)：386-404．
[2] 宁群， 舒斯云，包新民．大鼠纹状体边缘区和海马的功能联系研究[J]. 第一军医大学报，2002，22(8)：684-686．
[3] Brabec J，Kraseny J，Petrovicky P．Volumetry of striatum and pallidum in mananatomy，cytoarchitecture，connections，MRI and aging[J]．Sb Lek, 2003，104(1):13-65．
[4] Burwell RD. The parahippocampal region: corticocortical connectivity[J].Ann NY Acad Sci, 2000, (911) :25-42.
[5] Kawamura K, Yamasaki T , Kumata K, et al. Binding potential of (E)-[¹¹C] ABP688 to metabotropic glutamate receptor subtype 5 is by decreased the inclusion of its ¹¹C-labelled Z-isomer [J]. Nucl Med Biol, 2014,41 (1 ):17-23.
[6] Pievani M, Bocchetta M, Boccardi M, et al. Striatal morphology in early-onset and late-onset Alzheimer's disease: a preliminary study[J]. Neurobiol Aging, 2013, 34(7): 1728-1739.
[7] Raz N，Rodrigue K．Differential aging of the brain：patterns，cognitive correlates and modifiers[J]．Neurosci Biobehav Rev, 2006, 30(6)：730-748．
[8] Raz N，Rodrigue K，Kennedy KM，et a1．Differential aging of the human stiatum：longitudinal evidence[J]．AJNR Am J Neuroradiol，2003，24(9):1849-1856．
[9] 李月峰．海马体积、形态及其与抑郁症关系的MRI研究[D]．江苏大学，2009．
[10] 张海军，刘君. 立体定向健康中国人脑MRI海马结构体积的研究[J].中国实用医药，2009，4(11):56-57．
[11] 杜绪仓，王泽忠，鱼博浪，等．海马结构的磁共振体积测量[N].西安医科大学学报，2001，6 ( 3 ):210-2 l 1．
[12] Heimer L. Basal forebrain in the context of schizophrenia[J].Brain Res Rev, 2000, 31(2-3):205-235.
[13]杨琳.格氏解剖学38版（中文译版）[M].沈阳:辽宁教育出版社, 1999:1127-1128.
[14]de Jong LW, Wang Y, White LR, et al . Ventral striatal volume is associated with cognitive decline in older people: A population based MRI-study[J]. Neurobiol Aging, 2012, 33(2):424.e1-10.
[15] de Jong LW, vander K，Veer IM，et al．Strongly reduced volumes of putamen and thalamus in Alzheimer's disease：an MRI study[J]．Brain，2008，131(12)：3277-3285．
[16] Kaye JA，Moore MM, Dame A，et al．Asynchronous regional brain volume losses in presymptomatie to moderate AD[J].J Alzheimers Dis,2005,8(1)：51-56．
[17]孙钦建.颞叶癫痫大鼠认知功能与突触重塑相关蛋白表达的研究[D].山东大学，2009．
[18] Brandt GN, Bonelli RM. Structural neuroimaging of the basal ganglia in schi -zophrenic patients: a review[J]. Wien Med Wochenschr,2008,158(3-4):84-90.
[19]王丽，姚志剑，滕皋军，等．静息态下不同性别抑郁症患者脑功能及其差异的MRI研究[J]．中国心理卫生杂志，2008，24（4）：271-275.
[20] 汪启东，徐晓俊，张敏鸣．两侧内囊非对称性的磁共振弥散张量成像研究[J]． 浙江大学学报（医学版）.2008，37(5):472-476．
[21]徐敬峰，徐晓俊，汪启东，等．健康成人纹状体体积的磁共振在体测量研究[N]．浙江大学学报(医学版)，2010，39(2)：130-135．
[22] Alemda OP，Burton EJ，Mckeith I，et a1．MRI study of caudate nucleus volume in Parkinson’s disease withandwithout dementia with Lewy bodies and Alzheimer7s disease[J].Dement Geriatr Cogn Disord，2003,16(2):57-63．
[23] Xu J KS, Ymagucki S, Yamaguchi S,et a1.Gendereffects on age-related changes in brain structure [J].AJNR Am J Neuroradiol,2000,21(1):112-118．
[24] Pruessner JC, Li LM, Pruessner M, et a1．Volumetry of hippocampus and amygdala with high-resolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories[J]. Cereb Cortex, 2000 ,10(4): 433-442.
[25] 陈英敏，刘蓉辉，李宝山，等. 海马结构MRI三维分段方法[J].中国医学影像技术, 2005, 21(1):37-41.
[26] 刘智华，钱学华，周庭永，等. 基于MRI的人脑海马结构的形态测量[J]. 第三军医大学报, 2012, 34(16): 1636-1641.
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